ZNF32-AS2

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ZNF32-AS2 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ZNF32-AS2 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZNF32-AS2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF32-AS2 expression acts as an unfavorable survival marker, although some lineages such as UCS and HNSC show a favorable association.

KIRC, UCS, and HNSC are the cancer types where ZNF32-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileAll0.5550.719<.00183view →
UCSDFSMedianIV0.9520.367.00164view →
HNSCOSTertileII,III,IV0.4900.310.00261view →
BLCAOSMedianAll0.5270.353.00160view →
LIHCDFSQuartileAll0.3920.587<.00144view →
STADDFSMedianIV0.1210.669.00237view →
SKCMDFSQuartileAll0.2360.120.00136view →
PRADDFSQuartileAll0.6920.852.00234view →
CESCDFSMedianAll0.7810.858.01728view →
READOSMedianAll0.8370.292.00226view →
UVMDFSMedianIII,IV0.2080.740.00624view →
ACCDFSTertileAll0.4070.781.01615view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ZNF32-AS2–KIRC (DFS)

Kaplan–Meier survival curve for ZNF32-AS2 RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration