ZNF32-AS2

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ZNF32-AS2 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of ZNF32-AS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ZNF32-AS2 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF32-AS2 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, KIRC, and BLCA are the cancer types where ZNF32-AS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF32-AS2 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHFemaleIII,IV−0.790<.0018view →
KIRCAllAll+0.251<.0018view →
BLCAAllAll+0.520.0056view →
CHOLMaleAll+2.075<.0015view →
THCAAllII,III,IV−0.510.0055view →
LIHCAllAll+0.317<.0015view →
READAllAll+0.481.0232view →
UCECAllAll−0.426.0152view →
COADAllII,III,IV+0.295.0262view →
PRADAllAll+0.240.0322view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

ZNF32-AS2–KICH

Tumor-vs-normal expression box plot for ZNF32-AS2 RNA in KICH.

Open the KICH breakdown →

Exploration