ZNF319

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF319 mutation is significantly associated with the RNA expression of many other genes, with 426 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF319-associated genes across cancer lineages are ST13, DNAJC16, and DPH5. Each is linked with ZNF319 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF319-to-partner and partner-to-ZNF319 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ST13 grouped by ZNF319-low versus ZNF319-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF319→partner) and Y-score (partner→ZNF319) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEST13 →+0.584+3.321<.001.00332
LARGE_INTESTINEDNAJC16 →+0.596+3.502.002.00132
LARGE_INTESTINEDPH5 →+0.675+3.502<.001.00132
LARGE_INTESTINETTI2 →+0.641+3.307.001.00332
LARGE_INTESTINEHIPK4 →+0.076+3.761<.001<.00132
LARGE_INTESTINEPDIK1L →+0.548+3.502.007.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 426 associations by consensus.

ST13 by ZNF319 expression — LARGE_INTESTINE

Box plot of ST13 in ZNF319-low vs ZNF319-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration