ZNF317

Across TCGA cell cohorts, ZNF317 mutation is significantly associated with the RNA expression of many other genes, with 288 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF317-associated genes across cancer lineages are GALNT8, LZIC, and ZMYND10. Each is linked with ZNF317 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF317-to-partner and partner-to-ZNF317 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GALNT8 grouped by ZNF317-low versus ZNF317-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF317→partner) and Y-score (partner→ZNF317) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GALNT8 →	+1.068	+2.502	<.001	.005	3	2
LARGE_INTESTINE	LZIC →	+0.527	+3.628	.002	<.001	3	2
LARGE_INTESTINE	ZMYND10 →	+0.460	+3.321	<.001	.002	3	2
BLOOD_Lymphoma	SCGB1C1 →	+0.146	+4.714	<.001	.002	3	2
OESOPHAGUS	OR5AU1 →	+0.067	+4.017	.001	.007	3	1
OESOPHAGUS	OR51B6 →	+0.216	+4.017	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 288 associations by consensus.

GALNT8 by ZNF317 expression — LARGE_INTESTINE

Explore this box plot interactively →