Across TCGA pan-cancer cohorts, ZNF311 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated ZNF311 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher ZNF311 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF311 expression acts as an unfavorable survival marker.

SKCM are the cancer types where ZNF311 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	IV	0.415	0.861	.014	3	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: ZNF311 tumor-vs-normal RNA expression · all ZNF311 data types