ZNF311

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF311 mutation is significantly associated with the total protein of many other genes, with 33 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF311-associated genes across cancer lineages are EGFR_pY1068, eIF4E, and A-Raf_pS299. Each is linked with ZNF311 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF311-to-partner and partner-to-ZNF311 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF311→partner) and Y-score (partner→ZNF311) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECEGFR_pY1068 →-0.234-2.222.009.01033
UCECeIF4E →+0.164+3.183.030.00932
SKCMA-Raf_pS299 →-0.252-3.000.002.03632
UCECFOXO3a_pS318_S321 →-0.089-1.575.047.03432
UCECNotch1 →+0.185+2.817<.001.00132
UCECPCNA →+0.231+1.925.002.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

Exploration