Across TCGA cell cohorts, ZNF311 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF311-associated genes across cancer lineages are OR2T4, CT45A6, and PACRG. Each is linked with ZNF311 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF311-to-partner and partner-to-ZNF311 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF311→partner) and Y-score (partner→ZNF311) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	OR2T4 →	+0.033	+5.807	<.001	.001	3	1
OVARY	CT45A6 →	+0.040	+5.196	.003	.005	3	1
BLOOD_Leukemia	PACRG →	+0.285	+3.769	<.001	.004	3	1
BLOOD_Leukemia	CRHR1 →	+0.296	+3.995	<.001	.002	3	1
BLOOD_Leukemia	GHSR →	+0.017	+3.289	<.001	.009	3	1
BLOOD_Leukemia	BTBD16 →	+0.067	+3.959	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

Exploration

ZNF311 survival (RNA) · tumor vs normal (RNA) · all ZNF311 data types