ZNF302

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF302 mutation is significantly associated with the RNA expression of many other genes, with 2,406 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF302-associated genes across cancer lineages are MIR6780B, PPIAP88, and EIF3JP1. Each is linked with ZNF302 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF302-to-partner and partner-to-ZNF302 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6780B grouped by ZNF302-low versus ZNF302-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF302→partner) and Y-score (partner→ZNF302) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMIR6780B →+0.447+3.883.003.00632
CESCPPIAP88 →+0.099+3.413<.001.00632
UCECEIF3JP1 →+0.109+1.713.006.00632
UCECIGHD1-1 →+0.386+2.691<.001.00332
BLCARPS24P14 →+0.173+4.162<.001.00332
BLCAYWHAZP8 →+0.056+4.314<.001.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,406 associations by consensus.

MIR6780B by ZNF302 expression — BLCA

Box plot of MIR6780B in ZNF302-low vs ZNF302-high samples in BLCA.

Explore this box plot interactively →

Exploration