ZNF30

Across TCGA patient cohorts, ZNF30 mutation is significantly associated with the RNA expression of many other genes, with 1,657 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF30-associated genes across cancer lineages are RNA5SP402, CCNG1P1, and RER1. Each is linked with ZNF30 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF30-to-partner and partner-to-ZNF30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP402 grouped by ZNF30-low versus ZNF30-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF30→partner) and Y-score (partner→ZNF30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNA5SP402 →	+0.711	+4.503	<.001	.005	3	3
BLCA	CCNG1P1 →	+0.047	+4.704	<.001	.005	3	3
UCEC	RER1 →	+0.286	+2.732	.003	.003	3	2
UCEC	SMIM4 →	+0.486	+3.290	.001	<.001	3	2
UCEC	ABCF2 →	+0.361	+3.353	.008	.005	3	2
UCEC	RRP12 →	+0.396	+2.708	.005	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,657 associations by consensus.

RNA5SP402 by ZNF30 expression — LUSC

Explore this box plot interactively →