ZNF30

Across TCGA patient cohorts, ZNF30 mutation is significantly associated with the total protein of many other genes, with 21 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF30-associated genes across cancer lineages are INPP4B, Caspase-7-cleavedD198, and Cyclin-B1. Each is linked with ZNF30 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF30-to-partner and partner-to-ZNF30 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, INPP4B grouped by ZNF30-low versus ZNF30-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF30→partner) and Y-score (partner→ZNF30) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INPP4B →	-0.284	-2.321	.044	.034	3	2
UCEC	Caspase-7-cleavedD198 →	+0.600	+3.189	.020	.010	3	2
UCEC	Cyclin-B1 →	+0.622	+2.807	.011	.003	3	2
UCEC	ERK2 →	+0.235	+3.321	.005	.009	3	1
UCEC	GATA6 →	-0.155	-2.985	.026	.034	3	1
UCEC	Heregulin →	-0.122	-2.986	.024	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

INPP4B by ZNF30 expression — UCEC

Explore this box plot interactively →