ZNF287

Across TCGA pan-cancer cohorts, ZNF287 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZNF287 data layer compared with 21 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher ZNF287 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF287 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

CCRCC, LUAD, and PDAC are the cancer types where ZNF287 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.402	0.858	<.001	32	view →
LUAD	OS	Tertile	II,III,IV	0.440	1.000	.022	9	view →
PDAC	DFS	Median	IV	0.214	0.785	.006	9	view →
LSCC	DFS	Tertile	II,III,IV	0.887	0.198	.024	4	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ZNF287–CCRCC (DFS)

Open the CCRCC breakdown →