ZNF287

Across TCGA patient cohorts, ZNF287 mutation is significantly associated with the RNA expression of many other genes, with 4,577 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF287-associated genes across cancer lineages are PBK, TRAJ43, and NKAPD1. Each is linked with ZNF287 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF287-to-partner and partner-to-ZNF287 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PBK grouped by ZNF287-low versus ZNF287-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF287→partner) and Y-score (partner→ZNF287) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PBK →	+0.889	+2.283	<.001	<.001	3	3
COAD	TRAJ43 →	+0.619	+2.661	.002	.009	3	3
UCEC	NKAPD1 →	+0.301	+2.021	.008	<.001	3	3
UCEC	FAM126B →	+0.286	+2.110	.006	<.001	3	3
UCEC	CCNB2 →	+0.656	+1.999	<.001	<.001	3	3
UCEC	TYW5 →	+0.239	+2.010	.007	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,577 associations by consensus.

PBK by ZNF287 expression — UCEC

Explore this box plot interactively →