ZNF286B

Across TCGA patient cohorts, ZNF286B mutation is significantly associated with the RNA expression of many other genes, with 4,042 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF286B-associated genes across cancer lineages are NUDT4P2, SLC7A6OS, and SNX8. Each is linked with ZNF286B in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF286B-to-partner and partner-to-ZNF286B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NUDT4P2 grouped by ZNF286B-low versus ZNF286B-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF286B→partner) and Y-score (partner→ZNF286B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	NUDT4P2 →	+0.115	+3.222	<.001	.005	3	3
UCEC	SLC7A6OS →	+0.440	+1.888	<.001	<.001	3	3
UCEC	SNX8 →	+0.372	+2.180	<.001	<.001	3	3
UCEC	BAG1 →	+0.494	+1.765	<.001	<.001	3	3
COAD	ICMT →	+0.424	+3.486	<.001	.002	3	3
UCEC	SLC25A51 →	+0.284	+1.557	.004	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,042 associations by consensus.

NUDT4P2 by ZNF286B expression — LUSC

Explore this box plot interactively →