ZNF286B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF286B mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF286B-associated genes across cancer lineages are OR13D1, ELOA3DP, and OR13G1. Each is linked with ZNF286B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF286B-to-partner and partner-to-ZNF286B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13D1 grouped by ZNF286B-low versus ZNF286B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF286B→partner) and Y-score (partner→ZNF286B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEOR13D1 →+0.034+4.467<.001.00431
LARGE_INTESTINEELOA3DP →+0.023+4.273.003.00631
LARGE_INTESTINEOR13G1 →+0.024+4.415<.001.00731
LARGE_INTESTINEDEFA3 →+0.076+4.415<.001.00731
LARGE_INTESTINEOR6Q1 →+0.022+5.022<.001.00231
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR13D1 by ZNF286B expression — LARGE_INTESTINE

Box plot of OR13D1 in ZNF286B-low vs ZNF286B-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration