ZNF286B

Across TCGA cell cohorts, ZNF286B mutation is significantly associated with the mutation status of many other genes, with 491 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF286B-associated genes across cancer lineages are MAMDC2, OR2A25, and RBM22. Each is linked with ZNF286B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF286B-to-partner and partner-to-ZNF286B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAMDC2 grouped by ZNF286B-low versus ZNF286B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF286B→partner) and Y-score (partner→ZNF286B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAMDC2 →	+3.087	+4.392	.005	.005	1	2
LARGE_INTESTINE	OR2A25 →	+5.087	+4.523	.006	.006	1	2
LARGE_INTESTINE	RBM22 →	+5.087	+4.523	.006	.006	1	1
LARGE_INTESTINE	P2RX7 →	+3.350	+4.584	.003	.003	1	1
LARGE_INTESTINE	BRAP →	+2.865	+4.217	.007	.007	1	1
LARGE_INTESTINE	PLEKHG2 →	+2.865	+4.217	.007	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 491 associations by consensus.

MAMDC2 by ZNF286B expression — LARGE_INTESTINE

Explore this box plot interactively →