ZNF285

Across TCGA cell cohorts, ZNF285 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF285-associated genes across cancer lineages are MYF6, MMP27, and FSHR. Each is linked with ZNF285 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF285-to-partner and partner-to-ZNF285 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYF6 grouped by ZNF285-low versus ZNF285-high in OESOPHAGUS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF285→partner) and Y-score (partner→ZNF285) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	MYF6 →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	MMP27 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	FSHR →	+0.013	+4.906	<.001	.006	3	1
OESOPHAGUS	OR4E1 →	+0.016	+4.906	<.001	.006	3	1
OESOPHAGUS	CCDC195 →	+0.043	+4.906	<.001	.006	3	1
CNS	SELP →	+0.095	+3.774	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

MYF6 by ZNF285 expression — OESOPHAGUS

Explore this box plot interactively →