ZNF283

Across TCGA cell cohorts, ZNF283 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF283-associated genes across cancer lineages are TRIM42, PFN3, and TSPY2. Each is linked with ZNF283 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF283-to-partner and partner-to-ZNF283 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRIM42 grouped by ZNF283-low versus ZNF283-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF283→partner) and Y-score (partner→ZNF283) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	TRIM42 →	+0.006	+5.321	<.001	.005	3	1
CNS	PFN3 →	+0.078	+5.754	<.001	.002	3	1
LARGE_INTESTINE	TSPY2 →	+0.039	+3.632	<.001	.003	3	1
LARGE_INTESTINE	OR2Z1 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR5B21 →	+0.125	+3.977	<.001	.001	3	1
LARGE_INTESTINE	IQCF5 →	+0.025	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TRIM42 by ZNF283 expression — CNS

Explore this box plot interactively →