ZNF280C

Across TCGA patient cohorts, ZNF280C protein abundance is significantly associated with the RNA expression of many other genes, with 22,212 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF280C-associated genes across cancer lineages are TTK, VRK1, and GINS1. Each is linked with ZNF280C in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF280C-to-partner and partner-to-ZNF280C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF280C versus TTK in LSCC, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF280C→partner) and Y-score (partner→ZNF280C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TTK →	+1.297	+0.549	<.001	<.001	3	7
LSCC	VRK1 →	+1.032	+0.602	<.001	<.001	3	6
LSCC	GINS1 →	+1.028	+0.706	<.001	<.001	3	6
LSCC	CENPI →	+0.999	+0.699	<.001	<.001	3	6
HNSC	CENPF →	+1.215	+0.592	<.001	<.001	3	6
LUAD	KIF14 →	+1.019	+0.288	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,212 associations by consensus.

ZNF280C vs TTK — LSCC

Explore this scatter interactively →