ZNF280C

Across TCGA cell cohorts, ZNF280C mutation is significantly associated with the drug of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF280C-associated genes across cancer lineages are 50869, IAP_5620, and GSK2256098C. Each is linked with ZNF280C in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF280C-to-partner and partner-to-ZNF280C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 50869 grouped by ZNF280C-low versus ZNF280C-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF280C→partner) and Y-score (partner→ZNF280C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	50869 →	+0.442	+2.649	.037	.046	3	1
LARGE_INTESTINE	IAP_5620 →	+0.425	+2.649	.020	.046	1	1
LARGE_INTESTINE	GSK2256098C →	+0.391	+2.906	.010	.033	1	1
LARGE_INTESTINE	LMB_AB1 →	+0.308	+2.649	.040	.046	1	1
LARGE_INTESTINE	Bleomycin →	+0.458	+2.649	.021	.046	1	1
LARGE_INTESTINE	Gallibiscoquinazole →	+0.330	+2.649	.045	.046	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

50869 by ZNF280C expression — LARGE_INTESTINE

Explore this box plot interactively →