ZNF280B

Across TCGA patient cohorts, ZNF280B RNA expression is significantly associated with the protein abundance of many other proteins, with 13,023 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible ZNF280B-associated proteins across cancer lineages are TSPYL5, SLK, and KIF13B. Each is linked with ZNF280B in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF280B-to-partner and partner-to-ZNF280B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF280B versus TSPYL5 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF280B→partner) and Y-score (partner→ZNF280B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TSPYL5 →	+1.181	+0.966	<.001	<.001	3	4
HNSC	SLK →	-0.210	-0.659	.001	<.001	3	4
BRCA	KIF13B →	-0.576	-0.612	<.001	<.001	3	4
BRCA	ORC2_T226 →	+0.854	+0.810	<.001	<.001	3	4
PDAC	PTK6 →	-0.612	-0.490	<.001	<.001	3	4
LSCC	RAB6B →	+0.877	+0.885	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,023 associations by consensus.

ZNF280B vs TSPYL5 — LSCC

Explore this scatter interactively →