ZNF280B

Across TCGA patient cohorts, ZNF280B protein abundance is significantly associated with the RNA expression of many other genes, with 2,565 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ZNF280B-associated genes across cancer lineages are PES1, LGALS1, and POLR2F. Each is linked with ZNF280B in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF280B-to-partner and partner-to-ZNF280B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF280B versus PES1 in PDAC, with a Pearson correlation of 0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF280B→partner) and Y-score (partner→ZNF280B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	PES1 →	+0.260	+0.370	.001	.002	3	1
PDAC	LGALS1 →	+0.595	+0.432	<.001	<.001	3	1
PDAC	POLR2F →	+0.168	+0.341	.004	<.001	3	1
PDAC	TOMM22 →	+0.299	+0.270	.001	.003	3	1
PDAC	TIMP3 →	+0.832	+0.416	<.001	.002	3	1
PDAC	TOM1 →	+0.335	+0.411	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,565 associations by consensus.

ZNF280B vs PES1 — PDAC

Explore this scatter interactively →