ZNF280B

Across TCGA cell cohorts, ZNF280B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,863 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF280B-associated GO terms across cancer lineages are Calcium ion transport, Heterochromatin organization, and Heterochromatin formation. Each is linked with ZNF280B in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF280B-to-partner and partner-to-ZNF280B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Calcium ion transport grouped by ZNF280B-low versus ZNF280B-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF280B→partner) and Y-score (partner→ZNF280B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Calcium ion transport →	-0.063	-0.822	<.001	.002	3	9
OVARY	Heterochromatin organization →	+0.055	+0.617	<.001	<.001	3	9
OVARY	Heterochromatin formation →	+0.057	+0.633	<.001	<.001	3	9
OVARY	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.053	+0.732	<.001	.005	3	9
OVARY	mRNA splicing, via spliceosome →	+0.053	+0.732	<.001	.005	3	9
OVARY	Positive regulation of DNA repair →	+0.048	+0.806	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,863 associations by consensus.

Calcium ion transport by ZNF280B expression — OVARY

Explore this box plot interactively →