ZNF280A

Across TCGA patient cohorts, ZNF280A RNA expression is significantly associated with the protein abundance of many other proteins, with 9,353 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ZNF280A-associated proteins across cancer lineages are CAD, ZNF622_S143, and TPX2_S738. Each is linked with ZNF280A in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF280A-to-partner and partner-to-ZNF280A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF280A versus CAD in HNSC, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF280A→partner) and Y-score (partner→ZNF280A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CAD →	+0.274	+0.744	<.001	<.001	3	5
CCRCC	ZNF622_S143 →	+0.707	+0.195	<.001	.006	3	4
BRCA	TPX2_S738 →	+1.080	+0.427	<.001	<.001	3	4
HNSC	TOP2A →	+0.910	+0.976	<.001	<.001	3	4
LUAD	TOP2A_S1247 →	+0.885	+0.373	<.001	.003	3	4
LSCC	PNO1 →	+0.322	+0.619	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,353 associations by consensus.

ZNF280A vs CAD — HNSC

Explore this scatter interactively →