ZNF275

Across TCGA patient cohorts, ZNF275 mutation is significantly associated with the RNA expression of many other genes, with 4,465 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF275-associated genes across cancer lineages are NME1P1, ILKAP, and PSRC1. Each is linked with ZNF275 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF275-to-partner and partner-to-ZNF275 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, NME1P1 grouped by ZNF275-low versus ZNF275-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF275→partner) and Y-score (partner→ZNF275) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	NME1P1 →	+0.075	+4.485	<.001	.004	3	3
UCEC	ILKAP →	+0.226	+2.258	.002	<.001	3	3
UCEC	PSRC1 →	+0.492	+1.449	<.001	.003	3	3
COAD	THNSL2 →	-1.069	-3.584	.002	.002	3	3
UCEC	C3orf33 →	+0.295	+1.321	.003	.001	3	3
UCEC	RNU6-1213P →	+0.102	+2.526	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,465 associations by consensus.

NME1P1 by ZNF275 expression — SKCM

Explore this box plot interactively →