ZNF260

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF260 mutation is significantly associated with the RNA expression of many other genes, with 2,164 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF260-associated genes across cancer lineages are RNA5SP248, RN7SL303P, and RN7SL767P. Each is linked with ZNF260 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF260-to-partner and partner-to-ZNF260 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP248 grouped by ZNF260-low versus ZNF260-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF260→partner) and Y-score (partner→ZNF260) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNA5SP248 →+0.383+3.485<.001.00833
COADRN7SL303P →+0.384+5.602.004.00432
SKCMRN7SL767P →+0.289+3.214.002.00932
SKCMRNU6-313P →+0.237+2.906<.001.00532
SKCMSNORD3B-2 →+0.189+3.959.005.00132
SKCMRPL34P36 →+0.062+4.219<.001.00632
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,164 associations by consensus.

RNA5SP248 by ZNF260 expression — LUSC

Box plot of RNA5SP248 in ZNF260-low vs ZNF260-high samples in LUSC.

Explore this box plot interactively →

Exploration