ZNF260

Across TCGA cell cohorts, ZNF260 mutation is significantly associated with the mutation status of many other genes, with 539 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF260-associated genes across cancer lineages are TYRO3, FPR3, and GNAS. Each is linked with ZNF260 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF260-to-partner and partner-to-ZNF260 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TYRO3 grouped by ZNF260-low versus ZNF260-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF260→partner) and Y-score (partner→ZNF260) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TYRO3 →	+4.014	+4.969	.008	.008	1	3
BREAST	FPR3 →	+5.297	+5.297	.004	.004	1	2
BREAST	GNAS →	+4.297	+4.857	.009	.009	1	2
BREAST	ZNF30 →	+5.297	+5.297	.004	.004	1	2
BLOOD_Lymphoma	KDM2A →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	AARS1 →	+4.429	+5.247	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 539 associations by consensus.

TYRO3 by ZNF260 expression — BLOOD_Lymphoma

Explore this box plot interactively →