Across TCGA cell cohorts, ZNF251 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ZNF251-associated genes across cancer lineages are FUT9, KRTAP13-2, and GRXCR1. Each is linked with ZNF251 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF251-to-partner and partner-to-ZNF251 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF251→partner) and Y-score (partner→ZNF251) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	FUT9 →	+0.521	+3.823	.008	.006	3	1
SOFT_TISSUE	KRTAP13-2 →	+0.013	+4.392	<.001	.004	3	1
SOFT_TISSUE	GRXCR1 →	+0.054	+4.392	<.001	.004	3	1
SOFT_TISSUE	RPS4Y2 →	+0.019	+3.882	<.001	.004	3	1
LARGE_INTESTINE	TBC1D3 →	+0.057	+2.688	<.001	.008	3	1
LARGE_INTESTINE	TBC1D3C →	+0.968	+2.716	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

ZNF251 survival (RNA) · tumor vs normal (RNA) · all ZNF251 data types