ZNF232

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF232 mutation is significantly associated with the RNA expression of many other genes, with 1,250 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF232-associated genes across cancer lineages are RNU6-6P, VENTXP3, and RNU1-17P. Each is linked with ZNF232 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF232-to-partner and partner-to-ZNF232 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-6P grouped by ZNF232-low versus ZNF232-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF232→partner) and Y-score (partner→ZNF232) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU6-6P →+0.556+3.897<.001.00433
CESCVENTXP3 →+0.056+5.812<.001.00333
CESCRNU1-17P →+0.374+5.103<.001.00832
BLCAKLF17P1 →+0.106+3.867<.001.00432
BLCAMIR4654 →+0.264+4.444<.001.00632
UCECRPS29P32 →+0.453+2.406<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,250 associations by consensus.

RNU6-6P by ZNF232 expression — BLCA

Box plot of RNU6-6P in ZNF232-low vs ZNF232-high samples in BLCA.

Explore this box plot interactively →

Exploration