ZNF232

Across TCGA pan-cancer cohorts, ZNF232 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ZNF232 data layer compared with 2 for mutation status and 2 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher ZNF232 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF232 expression acts as an unfavorable survival marker, although some lineages such as KIRC and HNSC show a favorable association.

KICH, MESO, and KIRC are the cancer types where ZNF232 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	All	0.678	0.976	<.001	77	view →
MESO	DFS	Median	IV	0.155	0.498	<.001	66	view →
KIRC	DFS	Tertile	All	0.943	0.743	<.001	55	view →
KIRP	DFS	Median	IV	0.038	0.471	.010	38	view →
HNSC	DFS	Median	IV	0.712	0.568	.004	37	view →
ACC	DFS	Median	All	0.226	0.770	<.001	37	view →
LIHC	OS	Tertile	All	0.679	0.838	<.001	33	view →
PAAD	DFS	Median	All	0.380	0.179	.006	27	view →
LGG	DFS	Quartile	All	0.703	0.922	<.001	22	view →
CHOL	DFS	Quartile	All	0.117	0.733	.001	21	view →
SCLC	OS	Median	II,III,IV	1.000	0.421	.002	19	view →
LUSC	DFS	Quartile	III,IV	0.528	1.000	.025	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ZNF232–KICH (DFS)

Open the KICH breakdown →