ZNF232-AS1

Across TCGA pan-cancer cohorts, ZNF232-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated ZNF232-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher ZNF232-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF232-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and OV show a favorable association.

KIRC, MESO, and PAAD are the cancer types where ZNF232-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.551	0.699	<.001	140	view →
MESO	OS	Tertile	All	0.387	0.688	<.001	89	view →
PAAD	DFS	Quartile	All	0.530	0.254	.009	34	view →
LIHC	OS	Tertile	All	0.692	0.851	<.001	28	view →
LGG	DFS	Median	All	0.670	0.796	<.001	25	view →
UCS	DFS	Tertile	IV	0.250	0.814	.024	24	view →
ACC	OS	Median	All	0.425	0.804	<.001	19	view →
OV	OS	Median	III,IV	0.364	0.274	.011	18	view →
ESCA	OS	Median	II,III,IV	0.639	0.425	.006	16	view →
THYM	OS	Tertile	All	1.000	0.690	.006	16	view →
SKCM	OS	Quartile	All	0.760	0.845	.011	13	view →
LUSC	DFS	Quartile	III,IV	0.178	0.897	.007	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

ZNF232-AS1–KIRC (OS)

Open the KIRC breakdown →