ZNF232-AS1

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, ZNF232-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of ZNF232-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where ZNF232-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF232-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, LIHC, and THCA are the cancer types where ZNF232-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF232-AS1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KICHFemaleII,III,IV−1.595<.00111view →
LIHCMaleII,III,IV+1.499<.0019view →
THCAMaleIII,IV−1.187<.0019view →
KIRCMaleAll−0.483<.0019view →
UCECAllII,III,IV+0.910.0066view →
BRCAAllII,III,IV−0.312<.0016view →
HNSCAllAll+0.300.0045view →
LUSCAllAll+0.399.0024view →
CHOLAllAll+0.966<.0013view →
COADAllAll−0.253.0202view →
READAllAll−0.585.0211view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

ZNF232-AS1–KICH

Tumor-vs-normal expression box plot for ZNF232-AS1 RNA in KICH.

Open the KICH breakdown →

Exploration