ZNF229

Across TCGA cell cohorts, ZNF229 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,433 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF229-associated GO terms across cancer lineages are Cytoplasmic translation, Establishment of protein localization to organelle, and Spliceosomal tri-snRNP complex assembly. Each is linked with ZNF229 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF229-to-partner and partner-to-ZNF229 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by ZNF229-low versus ZNF229-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF229→partner) and Y-score (partner→ZNF229) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cytoplasmic translation →	+0.082	+1.785	<.001	<.001	3	10
OVARY	Establishment of protein localization to organelle →	+0.045	+1.160	.001	.009	3	9
SKIN	Spliceosomal tri-snRNP complex assembly →	+0.068	+1.460	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Establishment of protein localization to plasma membrane →	+0.127	+1.955	<.001	<.001	3	9
STOMACH	Sodium ion transmembrane transport →	-0.063	-1.602	.001	<.001	3	8
PANCREAS	Regulation of post-translational protein modification →	+0.040	+1.082	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,433 associations by consensus.

Cytoplasmic translation by ZNF229 expression — SKIN

Explore this box plot interactively →