ZNF226

Across TCGA patient cohorts, ZNF226 protein abundance is significantly associated with the protein abundance of many other proteins, with 1,564 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF226-associated proteins across cancer lineages are CCDC88C, ZNF646, and ZNF703. Each is linked with ZNF226 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF226-to-partner and partner-to-ZNF226 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF226 versus CCDC88C in HNSC, with a Pearson correlation of 0.59.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF226→partner) and Y-score (partner→ZNF226) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CCDC88C →	+0.533	+0.820	<.001	<.001	3	2
GBM	ZNF646 →	+1.420	+0.464	.001	.003	3	1
GBM	ZNF703 →	+0.906	+0.435	.002	.001	3	1
GBM	ZYX_S15 →	+0.807	+0.366	<.001	<.001	3	1
HNSC	BAHD1_S121 →	+0.794	+0.717	<.001	<.001	3	1
HNSC	C1orf21_S95 →	+0.571	+0.847	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,564 associations by consensus.

ZNF226 vs CCDC88C — HNSC

Explore this scatter interactively →