ZNF219

Across TCGA cell cohorts, ZNF219 mutation is significantly associated with the mutation status of many other genes, with 6,033 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF219-associated genes across cancer lineages are ABCA5, NOTCH4, and GAS2L2. Each is linked with ZNF219 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF219-to-partner and partner-to-ZNF219 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ABCA5 grouped by ZNF219-low versus ZNF219-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF219→partner) and Y-score (partner→ZNF219) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ABCA5 →	+4.415	+4.977	.007	.007	1	5
CNS	NOTCH4 →	+4.199	+5.347	<.001	<.001	1	4
OVARY	GAS2L2 →	+5.415	+5.415	.004	.004	1	4
BLOOD_Leukemia	CLSTN2 →	+3.498	+3.063	.006	.006	1	4
CNS	CRACD →	+4.614	+4.614	.006	.006	1	4
BLOOD_Leukemia	SYNPO2 →	+2.360	+2.741	.003	.003	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,033 associations by consensus.

ABCA5 by ZNF219 expression — OVARY

Explore this box plot interactively →