ZNF217

Across TCGA patient cohorts, ZNF217 mutation is significantly associated with the RNA expression of many other genes, with 4,760 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF217-associated genes across cancer lineages are TXNL4A, ALDOA, and RRP7A. Each is linked with ZNF217 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF217-to-partner and partner-to-ZNF217 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TXNL4A grouped by ZNF217-low versus ZNF217-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF217→partner) and Y-score (partner→ZNF217) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TXNL4A →	+0.343	+1.949	<.001	<.001	3	4
UCEC	ALDOA →	+0.429	+2.415	<.001	<.001	3	4
UCEC	RRP7A →	+0.367	+1.688	<.001	.001	3	4
UCEC	MINCR →	+0.448	+2.311	<.001	<.001	3	4
COAD	TNNC2 →	-2.659	-3.700	<.001	.001	3	3
UCEC	ADNP2 →	+0.556	+3.032	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,760 associations by consensus.

TXNL4A by ZNF217 expression — UCEC

Explore this box plot interactively →