ZNF217

Across TCGA cell cohorts, ZNF217 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,597 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF217-associated GO terms across cancer lineages are Positive regulation of stem cell population maintenance, Negative regulation of gene expression, epigenetic, and Heterochromatin formation. Each is linked with ZNF217 in more than 9 cancer types. Because this analysis shows association rather than direction, both ZNF217-to-partner and partner-to-ZNF217 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of stem cell population maintenance grouped by ZNF217-low versus ZNF217-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF217→partner) and Y-score (partner→ZNF217) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Positive regulation of stem cell population maintenance →	+0.061	+0.925	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Negative regulation of gene expression, epigenetic →	+0.052	+1.065	.004	.002	3	10
UPPER_AERODIGESTIVE_TRACT	Heterochromatin formation →	+0.047	+0.944	.004	.001	3	10
UPPER_AERODIGESTIVE_TRACT	CRD-mediated mRNA stabilization →	+0.095	+0.888	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Epigenetic regulation of gene expression →	+0.046	+1.050	.005	.001	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cytoplasmic mRNA processing body assembly →	+0.100	+0.888	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,597 associations by consensus.

Positive regulation of stem cell population maintenance by ZNF217 expression — SKIN

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