ZNF217

Across TCGA cell cohorts, ZNF217 mutation is significantly associated with the RNA expression of many other genes, with 522 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF217-associated genes across cancer lineages are MAGEB4, HELB, and ZNF557. Each is linked with ZNF217 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF217-to-partner and partner-to-ZNF217 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAGEB4 grouped by ZNF217-low versus ZNF217-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF217→partner) and Y-score (partner→ZNF217) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAGEB4 →	+0.007	+2.540	.003	.007	3	2
LARGE_INTESTINE	HELB →	+0.338	+3.087	.006	.006	2	3
LARGE_INTESTINE	ZNF557 →	+0.368	+3.169	.005	.009	3	2
LARGE_INTESTINE	GALNT1 →	+0.699	+3.169	.008	.009	3	2
LARGE_INTESTINE	FRA10AC1 →	+0.497	+3.743	.004	<.001	3	2
LARGE_INTESTINE	ZNF37A →	+0.656	+3.321	.003	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 522 associations by consensus.

MAGEB4 by ZNF217 expression — LARGE_INTESTINE

Explore this box plot interactively →