ZNF217

Across TCGA cell cohorts, ZNF217 mutation is significantly associated with the mutation status of many other genes, with 6,730 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF217-associated genes across cancer lineages are TRRAP, ITGB1, and INCENP. Each is linked with ZNF217 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF217-to-partner and partner-to-ZNF217 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRRAP grouped by ZNF217-low versus ZNF217-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF217→partner) and Y-score (partner→ZNF217) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TRRAP →	+2.162	+3.187	.009	.009	1	5
BLOOD_Lymphoma	ITGB1 →	+4.969	+4.014	.008	.008	1	5
BONE	INCENP →	+4.437	+5.000	.007	.007	1	4
LUNG_SCLC	SAMD9L →	+2.852	+3.608	.002	.002	1	4
BLOOD_Lymphoma	KLHDC7A →	+4.969	+4.014	.008	.008	1	4
LUNG_NSCLC_LUAD	OTOG →	+2.418	+3.079	.002	.002	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,730 associations by consensus.

TRRAP by ZNF217 expression — BLOOD_Lymphoma

Explore this box plot interactively →