ZNF213

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ZNF213 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF213-associated genes across cancer lineages are BMP15, KCNK17, and NTSR2. Each is linked with ZNF213 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF213-to-partner and partner-to-ZNF213 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BMP15 grouped by ZNF213-low versus ZNF213-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF213→partner) and Y-score (partner→ZNF213) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTBMP15 →+0.010+4.196<.001.00631
LARGE_INTESTINEKCNK17 →+0.051+3.333.005.00931
LARGE_INTESTINENTSR2 →+0.063+3.115<.001.00431
LARGE_INTESTINEOR10W1 →+0.009+3.562<.001.00231
LARGE_INTESTINEC14orf180 →+0.092+4.477.004<.00131
SKINSPAG11A →+0.044+4.437<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

BMP15 by ZNF213 expression — BREAST

Box plot of BMP15 in ZNF213-low vs ZNF213-high samples in BREAST.

Explore this box plot interactively →

Exploration