ZNF211

Across TCGA patient cohorts, ZNF211 mutation is significantly associated with the RNA expression of many other genes, with 1,851 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF211-associated genes across cancer lineages are MIR3115, NFKBIB, and C17orf98. Each is linked with ZNF211 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF211-to-partner and partner-to-ZNF211 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR3115 grouped by ZNF211-low versus ZNF211-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF211→partner) and Y-score (partner→ZNF211) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	MIR3115 →	+0.368	+4.424	<.001	.008	3	3
UCEC	NFKBIB →	+0.394	+1.949	<.001	.001	3	3
UCEC	C17orf98 →	+0.285	+1.521	.004	.007	3	2
HNSC	IGHD3-16 →	+1.211	+3.818	.002	.009	3	2
UCEC	ARHGEF40 →	-0.654	-2.223	<.001	.001	3	2
UCEC	TUB →	-0.722	-2.563	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,851 associations by consensus.

MIR3115 by ZNF211 expression — HNSC

Explore this box plot interactively →