ZNF211

Across TCGA pan-cancer cohorts, ZNF211 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated ZNF211 data layer compared with 6 for mutation status.

The strongest signal is observed in brain lower grade glioma (LGG), where higher ZNF211 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF211 expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

LGG, MESO, and BLCA are the cancer types where ZNF211 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	DFS	Median	All	0.645	0.825	<.001	54	view →
MESO	DFS	Median	IV	0.189	0.521	.002	48	view →
BLCA	OS	Median	II,III,IV	0.759	0.657	.008	35	view →
LUSC	DFS	Quartile	III,IV	0.566	0.830	.003	27	view →
BRCA	OS	Median	III,IV	0.891	0.770	.004	20	view →
CESC	DFS	Tertile	III,IV	0.421	0.766	.006	18	view →
SKCM	DFS	Median	III,IV	0.389	0.678	.002	18	view →
LIHC	DFS	Tertile	III,IV	0.153	0.379	.011	12	view →
GBM	DFS	Quartile	All	0.490	0.197	.004	12	view →
KIRC	DFS	Quartile	All	0.899	0.700	.003	11	view →
LUAD	OS	Quartile	All	0.496	0.251	.022	10	view →
THYM	DFS	Median	III,IV	1.000	0.402	.004	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

ZNF211–LGG (DFS)

Open the LGG breakdown →