ZNF211

Across TCGA patient cohorts, ZNF211 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF211-associated genes across cancer lineages are Caspase-7-cleavedD198, Caspase-8, and 14-3-3_beta. Each is linked with ZNF211 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF211-to-partner and partner-to-ZNF211 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by ZNF211-low versus ZNF211-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF211→partner) and Y-score (partner→ZNF211) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Caspase-7-cleavedD198 →	+0.869	+2.720	<.001	.003	3	2
UCEC	Caspase-8 →	-0.252	-2.780	.005	.003	3	2
UCEC	14-3-3_beta →	-0.079	-2.432	.028	.018	3	1
UCEC	eEF2 →	+0.383	+1.584	.002	.019	3	1
UCEC	EGFR_pY1068 →	-0.315	-2.415	<.001	.003	3	1
UCEC	eIF4E →	+0.158	+1.925	.037	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Caspase-7-cleavedD198 by ZNF211 expression — UCEC

Explore this box plot interactively →