ZNF211

Across TCGA cell cohorts, ZNF211 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF211-associated genes across cancer lineages are IQCF6, LMX1A, and SPATA19. Each is linked with ZNF211 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF211-to-partner and partner-to-ZNF211 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF6 grouped by ZNF211-low versus ZNF211-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF211→partner) and Y-score (partner→ZNF211) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	IQCF6 →	+0.118	+4.977	<.001	.007	3	2
KIDNEY	LMX1A →	+0.006	+5.000	<.001	.005	3	1
KIDNEY	SPATA19 →	+0.036	+5.000	<.001	.005	3	1
BLOOD_Leukemia	CFC1 →	+0.014	+4.539	<.001	.007	3	1
BLOOD_Leukemia	GPR26 →	+0.057	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR1L3 →	+0.070	+4.276	.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

IQCF6 by ZNF211 expression — SKIN

Explore this box plot interactively →