ZNF200

Across TCGA cell cohorts, ZNF200 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF200-associated genes across cancer lineages are MT4, OPN1MW, and MAGEB4. Each is linked with ZNF200 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF200-to-partner and partner-to-ZNF200 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MT4 grouped by ZNF200-low versus ZNF200-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF200→partner) and Y-score (partner→ZNF200) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	MT4 →	+0.172	+5.169	<.001	.005	3	1
BREAST	OPN1MW →	+0.049	+5.169	<.001	.005	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+5.415	.009	.004	3	1
LARGE_INTESTINE	OR10W1 →	+0.019	+4.977	<.001	.007	3	1
BLOOD_Leukemia	GH2 →	+0.017	+4.384	<.001	.006	3	1
BLOOD_Leukemia	TEX47 →	+0.036	+4.269	.006	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MT4 by ZNF200 expression — BREAST

Explore this box plot interactively →