ZNF2

Across TCGA cell cohorts, ZNF2 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible ZNF2-associated genes across cancer lineages are CABP2, KCNG4, and TRIM49B. Each is linked with ZNF2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF2-to-partner and partner-to-ZNF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CABP2 grouped by ZNF2-low versus ZNF2-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF2→partner) and Y-score (partner→ZNF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	CABP2 →	+0.016	+4.029	<.001	.007	3	1
PANCREAS	KCNG4 →	+0.008	+4.029	<.001	.007	3	1
PANCREAS	TRIM49B →	+0.018	+4.029	<.001	.007	3	1
PANCREAS	FAM9A →	+0.024	+3.786	<.001	.004	3	1
PANCREAS	KRTAP19-5 →	+0.190	+3.786	<.001	.004	3	1
PANCREAS	MOG →	+0.082	+3.750	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

CABP2 by ZNF2 expression — PANCREAS

Explore this box plot interactively →