ZNF197-AS1

Across TCGA pan-cancer cohorts, ZNF197-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated ZNF197-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher ZNF197-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF197-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and LAML show a favorable association.

UCS, KICH, and LAML are the cancer types where ZNF197-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Quartile	II,III,IV	0.650	0.168	<.001	104	view →
KICH	OS	Tertile	II,III,IV	0.492	1.000	.015	57	view →
LAML	DFS	Tertile	All	0.606	0.241	.002	28	view →
UVM	OS	Quartile	All	0.798	0.412	.023	17	view →
SKCM	DFS	Quartile	II,III,IV	0.194	0.599	.003	16	view →
PRAD	OS	Median	All	0.771	0.991	.004	14	view →
KIRP	DFS	Tertile	II,III,IV	0.787	0.379	.017	13	view →
SARC	OS	Median	All	0.450	0.724	.010	12	view →
UCEC	DFS	Quartile	All	0.775	0.885	.004	8	view →
LUSC	OS	Quartile	All	0.851	0.557	.004	6	view →
KIRC	DFS	Median	IV	0.178	0.403	.032	4	view →
CESC	DFS	Tertile	III,IV	0.194	0.793	.014	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

ZNF197-AS1–UCS (DFS)

Open the UCS breakdown →