ZNF197-AS1

Across TCGA pan-cancer cohorts, ZNF197-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of ZNF197-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where ZNF197-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF197-AS1 is over-expressed in tumor, although a few such as KIRC and THCA show the opposite, repressed pattern.

KIRC, THCA, and KICH are the cancer types where ZNF197-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF197-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−0.872	<.001	12	view →
THCA	Male	III,IV	−0.918	<.001	11	view →
KICH	Female	All	−1.106	<.001	7	view →
BLCA	Female	All	+0.490	.013	6	view →
COAD	Female	III,IV	−0.462	.031	4	view →
BRCA	Female	All	−0.217	<.001	4	view →
CHOL	All	All	+0.654	<.001	3	view →
READ	All	II,III,IV	−0.625	.011	3	view →
LUSC	All	All	+0.319	<.001	3	view →
UCEC	All	All	−0.438	.001	2	view →
KIRP	Male	All	−0.335	.008	2	view →
PRAD	All	All	−0.229	.007	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

ZNF197-AS1–KIRC

Open the KIRC breakdown →