ZNF195

Across TCGA cell cohorts, ZNF195 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,806 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF195-associated GO terms across cancer lineages are Replication fork processing, Positive regulation of double-strand break repair, and Regulation of DNA recombination. Each is linked with ZNF195 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF195-to-partner and partner-to-ZNF195 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Replication fork processing grouped by ZNF195-low versus ZNF195-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF195→partner) and Y-score (partner→ZNF195) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Replication fork processing →	+0.108	+0.840	.003	.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of double-strand break repair →	+0.083	+1.110	<.001	<.001	3	12
BONE	Regulation of DNA recombination →	+0.077	+0.825	.006	.004	3	11
BONE	Regulation of double-strand break repair →	+0.071	+0.901	.003	<.001	3	11
BONE	Positive regulation of DNA repair →	+0.065	+0.866	.002	.002	3	11
SOFT_TISSUE	Negative regulation of gene expression, epigenetic →	+0.075	+1.385	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,806 associations by consensus.

Replication fork processing by ZNF195 expression — BLOOD_Myeloma

Explore this box plot interactively →