ZNF195

Across TCGA pan-cancer cohorts, ZNF195 RNA is linked to patient survival in 28 of 34 cancer types, making it the most broadly survival-associated ZNF195 data layer compared with 5 for mutation status.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ZNF195 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ZNF195 expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

ACC, KICH, and BLCA are the cancer types where ZNF195 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.202	0.705	<.001	88	view →
KICH	DFS	Tertile	II,III,IV	0.600	1.000	.002	79	view →
BLCA	OS	Median	All	0.521	0.321	<.001	75	view →
LIHC	DFS	Tertile	All	0.446	0.628	<.001	61	view →
BRCA	DFS	Tertile	All	0.966	0.921	.006	44	view →
READ	OS	Tertile	II,III,IV	0.752	0.292	.007	23	view →
LGG	OS	Median	All	0.516	0.344	<.001	21	view →
LUSC	DFS	Tertile	III,IV	0.137	0.771	.007	18	view →
THYM	DFS	Quartile	All	0.837	0.608	.005	12	view →
STAD	DFS	Median	II,III,IV	0.313	0.620	.015	12	view →
MESO	OS	Tertile	IV	0.834	0.296	.011	12	view →
UVM	DFS	Quartile	III,IV	0.234	0.832	.004	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 28 lineages.

ZNF195–ACC (DFS)

Open the ACC breakdown →