ZNF195

Across TCGA cell cohorts, ZNF195 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF195-associated genes across cancer lineages are ASB17, ZP2, and ZP4. Each is linked with ZNF195 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF195-to-partner and partner-to-ZNF195 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASB17 grouped by ZNF195-low versus ZNF195-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF195→partner) and Y-score (partner→ZNF195) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	ASB17 →	+0.023	+5.807	<.001	.001	3	1
BLOOD_Leukemia	ZP2 →	+0.158	+4.409	<.001	.005	3	1
BLOOD_Leukemia	ZP4 →	+0.012	+4.539	<.001	.007	3	1
BLOOD_Leukemia	ASZ1 →	+0.145	+4.152	<.001	.009	3	1
BLOOD_Leukemia	CNGB3 →	+0.106	+4.152	.005	.009	3	1
BLOOD_Leukemia	CFHR2 →	+0.306	+6.124	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

ASB17 by ZNF195 expression — OVARY

Explore this box plot interactively →